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Contents:

• Reviews on Postoperative Nausea and Vomiting
• Drug Monographs

The information (eg trade names and dosage schedules) supplied in some of these pages may be very specific to a particular country (for example Fiorinal contains completely different agents in the USA and Australia). Please keep this in mind and consult local information guides if in doubt.

Reviews on Postoperative Nausea and Vomiting

Disclaimer: The guidelines on drug usage in the following articles do not necessarily represent my own views on the treatment of PONV.

The Virtual Hospital in Iowa has an article entitled Management of Postoperative Nausea and Vomiting: The Role of Droperidol, Metoclopramide, and Ondansetron by Douglas Morgan. It is mainly a set of guidelines on the use of drugs, mainly those listed in the title, for both prophylaxis and rescue.

Robert Langer also has a review (ascii text) on Postoperative Nausea and Vomiting in Educational Synopses in Anesthesiology and Critical Care Medicine. You can also have it in german.

Drug Monographs

The following monographs are courtesy of MIMS (Australia) Online (subscription required) which has a section devoted to antiemetics/antinauseants, RxMed and Nursespdr. Each of these contains monographs for thousands of drugs of all types and MIMS can be searched by trade and generic name. I have listed only those drugs commonly used for PONV and for which monographs are currently available. Unfortunately, I have recently discovered that MIMS requires subscrition for most people. Those within the 'edu.au' domain seem to have free access (hence the fact that I didn't know!). Also, people working in Australian public hospitals can get free passwords via the CIAP website. Until I find a suitable alternative, I will leave the MIMS links as they are.

Drug Name	MIMS	RxMed	Nursespdr
Chlorpromazine	Largactil, Chlorpromazine Injection BP	chlorpromazine	chlorpromazine
Dexamethasone			dexamethasone
Dimenhydrinate	Dramamine, Travacalm	Dimenhydrinate Injection	dimenhydrinate
Dolasetron	Anzemet	Anzemet	dolasetron
Droperidol	Droleptan		droperidol
Granisetron		Kytril	granisetron
Metoclopramide	Maxolon, Metoclopramide Injection, Metoclopramide Injection BP, Metoclopramide Injection BP, Pramin		metoclopramide
Ondansetron	Zofran	Zofran	ondansetron
Prochlorperazine	Stemetil	Stemetil
Promethazine	Avomine, Insomn-Eze, Phenergan, Promethazine HCl Injection BP	Phenergan, Phenergan Injectable, Phenergan Preparations	promethazine
Tropisetron	Navoban

This chapter is kindly sponsored by Wavelength Consulting International Medical Recruitment and Locum Service. We are most grateful for their assistance.

Questions about the Virtual Anaesthesia Textbook project itself should be e-mailed to Chris Thompson.