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Contents: A First Course in Pharmacokinetics and Biopharmaceutics: The basics of kinetics. Starts with mathematical equations and relations and leads you to the related applications in medical and pharmaceutical applications. The best theoretical approach to the theme I know. Clinical Pharmacology is a useful section of the Merck Manuals. It contains 9 sub-chapters dealing with basics as drug input and disposition, pharmacokinetics, pharmacodynamics and drug toxicity as well as drug monitoring or drug therapy in the elderly. Context Sensitive Decrement Times: This site explains how the nature of a drug and the duration of an infusion influences the offset of the drug effect. Examples include narcotics and general anaesthetic agents. Pharmacokinetic and pharmacodynamic resources: This page provides a link to the PharmPK-mailing list with links to other pharmacology related sites. Stanford's pharmacokinetic and pharmacodynamic software: On this server you will find a repository of NONMEM routines, other PK/PD software, computer controlled drug administration programs, and simulation programs. (NONMEM means non-linear mixed effects models!) PK Equations provides pharmacological constants and calculus. Virtual Pharmacy Center - Martindale's Health Science Center: A very comprehensive collection of links for pharmacists and chemists primarily. The Periodic Table of the Elements (WebElements) with atomic data. UK FRCA notes on local anaesthetic pharmacology and a page on the use of lipid solutions to treat toxicity.
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